The physiological photodegradation of sunscreen filters follows a predictable pattern once normalization to the starting SPF value is considered. This baseline aids in predicting SPF loss over time and supports sunscreen formulation research and development.

By understanding photodegradation, we can improve in-use behavior and prevent consumer harm. Additionally, this knowledge could lead to a correction factor for in vitro SPF measurements, potentially replacing costly and ethically challenging in vivo tests.

While current in vitro methods lack reliability due to various real-life variables, addressing photostability is a crucial step towards a more efficient and ethical SPF testing process.

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Abich

Agnès Malartre

agnes.malartre@abich.it

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