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Skin Challenges 2018, for future vision & trends of how can the current research delay the side effects of ageing and skin-ageing?

Hot topics will be discussed: skin ageing mechanisms, mitochondria, Nrf2 modulation, gut and skin microbiota inter-talk, smell and olfactory receptors, exposomes and others…

Aims of Skin Challenges 2018 are to:

– Draft the state of the art in skin ageing

– Present the different mechanisms involved in homeostasis and skin aging but also to address the different tracks and pathways (signaling, transcription factors…) involved in this process

– Highlight the recent innovations in skin ageing and photo ageing

– Presenting the new notion of exposome and skin aging

– What are the internal and external factors that we can qualify as exposome?

– What is the response of the body and the skin barrier to these internal and external factors?

– What is the current state of knowledge about the interaction of distinct exposomal factors with each other and what is the resulting effect on skin aging?

– How to determine the influence of these exposomes on skin aging?

– Which kind of protective measures should be considered to limit cutaneous aging?

– What is the strategic role of skin olfactory receptors and smell

– How to explain the regeneration and cicatrisation by olfacory receptors activation?

– What is the impact of smell on skin ageing?

– What is the impact of smell on skin ageing?

– Discuss the role of microbiota and skin microbiota

– What is the role of gut microbiota and skin microbiota on skin ageing?

– What is the importance of quality and diversity of microbiota on skin barrier?

– What are the factors (pre/probiotics, bacteria…) able to influence the skin microbiota?

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