Researchers from the University of Zaragoza have employed the Be-Transflow device to develop a stratified epithelia-on-a-chip model, highlighting this device as a useful platform for permeability studies.
Replicating the permeability of a tissue barrier is pivotal in evaluating the selective transport of substances, such as chemicals, drugs or cosmetics, through epithelial tissues. The capacity of substances to cross tissue barriers influences their absorption into the bloodstream and effectiveness. Hence, determining the permeability of a substance in the pharmaceutical or cosmetic industry is paramount, especially in toxicological studies. Here, we review a scientific publication of the TME Lab, in which the team lead by Jesus Ciriza uses the BE-Transflow as a novel platform for permeability studies.
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