Aging skin, vulnerable to age-related defects, is poor in wound repair. Metabolic regulation in accumulated senescent cells (SnCs) with aging is essential for tissue homeostasis, and adequate ATP is important in cell activation for aged tissue repair.
Strategies for ATP metabolism intervention hold prospects for therapeutic advances. Here, we found energy metabolic changes in aging skin from patients and mice.
Our data show that metformin engineered EV (Met-EV) can enhance aged mouse skin repair, as well as ameliorate cellular senescence and restore cell dysfunctions.
Kristel Adriaenssens Milet 1 April 2025 Social intelligence company Dynvibe, which specialises in behavioural marketing…
26 March 2025 The 35th IFSCC Congress will take place in Cannes from September 15…
This AI-powered skin diagnostic device uses bio-optical technology alongside AI algorithms to analyze the skin’s…