Europe

In Vivo Method for Evaluating Sunscreen Protection Against High-energy Visible Light via National Library of Medicine

Background: Overexposure to sunlight can have many harmful biological effects on the skin, leading to skin cancer and photoaging. As ultraviolet (UV) radiation has been identified as a cause of DNA damage and oxidative stress in the skin, the photoprotection provided by sunscreens is evaluated through their ability to filter UV light, using the sun protection factor (SPF). However, recent data have shown that high-energy visible (HEV) light can also cause biological skin damage.

Objectives: To develop a new in vivo method for evaluating the protection provided by sunscreens across a broad range of wavelengths, including the HEV band, based on multispectral image analysis.

Methods: This study evaluated the absorption properties of six commercially available sunscreens (five SPF 50+ products containing organic UV filters, and one product containing the wide spectrum filter, phenylene bis-diphenyltriazine [TriAsorB™]) and of a control product containing no filter.

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