The C-Cube: a unique tool to validate your claims by Pixience

4 April 2025

In the cosmetics sector, innovation and scientific rigour are essential. Laboratories must rely on accurate evaluation methods to validate their anti-aging claims.

Wrinkles, pigment spots or alteration of skin texture: these criteria must be measured reliably to be validated.

The C-Cube: a unique tool to validate your claims

The C-Cube is an essential reference for the scientific validation of claims in dermocosmetics. The only microdermoscopic imager on the market, it captures a precisely defined area and offers an analysis of unparalleled finesse.

Unlike macro and semi-macro imagers, the C-Cube reveals skin structures with optimal resolution, allowing for a detailed assessment of the effects of care. It also differs from probes by offering a complete and in-depth visualization of the skin. At the crossroads of these technologies, it is a unique and complementary tool, guaranteeing a rigorous and reproducible evaluation.

Thanks to its high-precision color calibration, perfectly correlated with a chromameter, it ensures reliable and consistent measurements. Its homogeneous indirect illumination eliminates distortion and loss of information at the edges of the image, ensuring consistent analysis across the entire observed area.

Finally, the C-Cube integrates high-resolution 3D imaging based on stereophotometry, an advanced technology that allows for fine-grained analysis of skin topography.

Thanks to its 2D and 3D imaging capabilities, the C-Cube offers a detailed analysis of key markers of skin aging, thus enhancing the accuracy and reliability of dermocosmetic studies.

Evaluation of anti-aging effects with the C-Cube 3 CR

1. Pigmentation and homogeneity

Exposure to the sun and certain chemical agents can affect melanin production and result in dark spots with age and a decrease in the evenness of the skin tone.

Anti-dark spot, depigmenting or whitening treatments are then developed to meet this criterion.

To measure the effects of this care, the C-Cube 3 CR is a tool with high added value. Thanks to its illumination and color calibration, it provides a pigmentation index, based on the melanin content of the skin. This index allows an objective measurement.

Pigmentation measurement with the C-Cube

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It may also be interesting to evaluate the homogeneity of the pigmentation. This approach is particularly relevant for skin where the spots are not isolated but dispersed in a diffuse way, which is common with skin aging.

To quantify this homogeneity of skin tone, we study the variance of the amount of melanin in the image. The higher the variance, the more irregular the skin pigmentation. A decrease in this value over time results in a more even complexion, thus making it possible to objectify the effectiveness of corrective treatments.

2. 3D parameters

a. Roughness

Skin roughness is a key parameter in the evaluation of skin aging. With age, the decrease in collagen and elastin production leads to a loss of firmness and elasticity, promoting the appearance of irregularities on the surface of the skin. These irregularities manifest themselves in the form of accentuated micro-reliefs, wrinkles and fine lines, contributing to an alteration of the skin texture.

Thanks to the C-Cube technology, it is possible to extract quantitative parameters such as Sa (average roughness), Sq (quadratic roughness) and Sdr (relative surface development), providing a detailed view of changes in skin relief. A decrease in these values reflects a smoothing of the skin surface, a sign of an effective anti-aging effect.

b. Wrinkle Depth

The evaluation of the effectiveness of an anti-aging product can involve measuring the depth of wrinkles.

Stereophotometry allows the calculation of the following quantitative parameters:

– Sv (Maximum Valley Depth): A high value of Sv indicates a more pronounced and deeper wrinkle. Its analysis is relevant for evaluating the effectiveness of a filler with significant effects, such as injectables.
– Sz (gap between peaks and troughs of a surface): This value is used to quantify a change in the overall condition of the skin’s relief.

By integrating Sv and Sz measurements, it is possible to demonstrate the reduction in wrinkle depth after product application, validating marketing claims with rigorous data.

c. Profilometry Module

The C-Cube’s profilometry module offers an advanced approach for the quantitative analysis of wrinkles and skin reliefs. Thanks to the ability to draw a region of interest (ROI) as a broken line, it allows you to accurately track variations in skin structures depending on the treatment applied.

On the followed wrinkle, we provide essential data such as the volume of the wrinkle, its length or its microrelief.

Thanks to the combined analysis of 2D and 3D parameters, the C-Cube offers a quantitative, objective and comprehensive evaluation of the effects of skin aging. It thus makes it possible to measure the effectiveness of anti-aging treatments with unparalleled rigour.

A true reference for these analyses, it guarantees precise and reproducible results, thus strengthening the reliability of clinical studies. Its qualitative illustrations also facilitate the communication of results to marketing teams, providing clear and verifiable data.

In a highly competitive market, the C-Cube is an essential ally for the validation and enhancement of anti-aging treatments.