Scientifically Testing the Effect of Cosmetic Products on Skin and Hair Microbiota by Monasterium Laboratory

23 February 2023

Our skin and hair follicles harbour unique ecosystems consisting of millions of bacteria, fungi, mites, and viruses: the skin and hair microbiotas, which greatly affect skin and hair health. In this sense, it is long accepted that dysbiosis is associated with various skin and hair diseases (i.e. atopic dermatitis, seborrheic dermatitis, psoriasis, dandruff, acne vulgaris, acne inversa, alopecia areata, androgenetic alopecia, and more).

Therefore, it is not surprising that the number of cosmetic products aiming to rebalance or protect the microbiome (e.g. pre- and probiotics and nutraceuticals) is increasing. They, at Monasterium Laboratory, combine their expertise and knowledge in dermatological, trichological and microbiological research to develop comprehensive analysis of the skin and hair microbiome in human samples ex vivo – to guide your research on active ingredients and cosmetic formulations and support cosmetic product claims.

Their expertise includes basic microbiology testing (e.g. agar diffusion assays), high-throughput sequencing techniques and multi-omic technologies that allow analysis and characterisation of the genomes of various microorganisms including bacteria, viruses/phages and fungi. If combined with Laser-Capture Microdissection they can investigate the different sets of microbes in specific skin and hair follicle compartments (even within deep tissue layers). Through this, they can specifically analyse either skin or hair follicle microbiota without cross-contamination.

The detailed understanding of microbiome composition and the interaction of microbiota metabolites with skin and hair follicle cells is essential to develop effective active cosmetic ingredients that give benefits in skin and hair appearance without adversely disturbing the microbiome.

They offer a comprehensive package of solutions to investigate how formulations and active ingredients impact on the diversity of microbes, antimicrobial peptide secretion and the resulting consequences for skin and hair follicle biology and immunity. For example, they have examined how changes in the microbiome composition of the hair follicle by antibiotic treatment affects hair growth, and how topical application of the synthetic sandalwood odorant Sandalore® affects microbiota viability and production of antimicrobial peptides in human skin ex vivo.

Check out all their scientific publications on the skin and hair follicle microbiome here.

Access the poster about changes in the human scalp hair follicle microbiome here: Flyer – Human scalp hair follicle and skin microbiome ex vivo Monasterium Laboratory

Meet us personally in stand AA40 at this year’s in-cosmetics global in Barcelona.

Stay tuned on LinkedIn and regularly visit our Website for more information.

 

CONTACT

Dr. Leslie Ponce

Business Development Assistant

Phone: +49 251 93132951

email: l.ponce@monasteriumlab.com

Monasterium Laboratory
Skin & Hair Research Solutions GmbH
Nano-Bioanalytik Zentrum
Mendelstraße 17
D-48149 Münster, Germany

Phone:  +49 (0) 251 93263-080

www.monasteriumlab.com


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