BioDan Sciences’ bioprinted human skin test model features an innovative and well-differentiated epidermis with stratum corneum, a bilayer of reconstructed human epidermis and dermis cultured on a fibrin matrix. A dermal layer containing human collagen produced by fibroblasts and a basal membrane containing collagen VII is placed between the epidermal and dermal compartments.
Our model is capable of reproducing normal human skin and is therefore an ideal alternative to in vitro drug and vehicle screening. Human keratinocytes are obtained from healthy consenting donors through human biopsies. They are then expanded and cultured via a process allowing for differentiation to produce stratum corneum.
Our testing model has been developed in line with ECVAM standards and focuses on the development of the following test assays:
The skin is densely innervated by a complex network of nerve fibers responsible for detecting…
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Georgina Caldwell 28 February 2025 THE WHAT? Shiseido’s patented, proprietary optical clearing technique, which makes skin…