June 20-21 2018
The Westin Copley Place, Boston M A
Inadequate representation of the human tissue environment during a preclinical screen can result in inaccurate predictions of a drug candidate’s effects. Thus, pharmaceutical investigators are searching for preclinical models that closely resemble original tissue for predicting clinical outcome.
Three-dimensional cell culture recapitulates normal and pathological tissue architectures that provide physiologically relevant models to study normal development and disease. However, challenges remain for high-throughput screening as researchers must procure large numbers of identical 3D cell cultures, develop assays and obtain fast, automated readouts from these more complex assays.
Join cell biologists, tissue engineers, assay developers, screening managers and drug developers at Cambridge Healthtech Institute’s Fourth Annual 3D Cellular Models: Engineering Predictive Preclinical Screening Models conference as they discuss strategies that accelerate the identification of novel therapeutic leads.