BASF and CTIBiotech evolve 3D skin model to enable anti-inammatory analysis via Cosmetics Design Europe

Produced by Kacey Culliney, 5 sept 2019

Specialty chemicals major BASF and research institute CTIBiotech have created another 3D skin model with immune macrophages to enable R&D work into anti-inammatory ingredients. The two rms previously developed a 3D bio-printed skin model with human sebaceous glands for research into sebum production and regulation.

In early 2018, following two years in development, BASF and CTIBiotech said experts demonstrated ex vivo production of physiological sebum in a long-term culture of the 3D human sebaceous gland model and the regulation of this sebum production through active ingredients.

An anti-inammatory twist

Annika Bröter, communications manager for BASF Personal Care Europe, said the technology behind the 3D bio-printing for this latest skin model was the same, but the research focus dierent. “It’s a completely dierent focus, new model and new project,” Bröter told CosmeticsDesign-Europe. This skin model included immune macrophages – important for tissue regeneration and suppressing inammation – and therefore enabled research into the anti-inammatory properties of active ingredients.

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