Working with the Institute for In Vitro Sciences (IIVS), two major players in the ingredients manufacture and supply for the beauty and personal care industry are teaming up to work on animal testing alternatives.
Givaudan and BASF are working with the IIVS to validate an improved skin sensitization reactivity method to address the needs of toxicologists and regulators.
The test they are working on is called the Kinetic Direct Peptide Reactivity Assay (Kinetic DPRA). It aims to be a non-animal test to predict allergic reactions in the skin (known as skin sensitization).
It is a next level test, according to the parties involved, meaning non-animal testing methods can now become much more sophisticated.
“Three other non-animal sensitizer tests have been internationally accepted,” they explain. “However, the Kinetic DPRA has the potential to go beyond a yes/no answer and predict the potency of a sensitizer, which is required by some regulatory agencies. Until now the only way to predict potency classifications was through animal testing.”
Other participating laboratories include The Procter & Gamble Company (developer of the original DPRA), Charles River and the Czech National Institute of Public health….