Comparison of facial skin ageing in healthy Asian and Caucasian females quantified by in vivo line-field confocal optical coherence tomography 3D imaging via Wiley

Quantitative biomarkers of facial skin aging were investigated in 109 healthy Asian female volunteers, aged 20 to 70 years.

In vivo 3D Line-field Confocal Optical Coherence Tomography (LC-OCT) imaging, enhanced by AI-based quantification algorithms, was utilized to compute various metrics.

Specific findings emerged, such as larger, more heterogeneous nuclei in both layers, demonstrated by an increase in nuclei volume and their standard deviation, and increased network atypia.

Ethnicity-wise comparisons highlighted distinct biological features specific to each population.