Genoskin brings unique alternative to animal testing to the US

5 September 2017

Skin biotech to set up Boston production unit that recycles excess human skin


Toulouse, France, August 29, 2017 Genoskin, a company that provides a cutting-edge alternative to animal testing by keeping donated human skin alive, today announces its expansion into North America. The biotech has established a representative office in Boston and plans to open a local production unit in the first quarter of 2018.

Genoskin provides a unique alternative to animal testing using excess human skin that is kept alive in testing wells. The skin is donated by patients after common plastic surgery procedures, such as tummy tucks. At the end of these procedures, any excess skin is generally disposed of by the hospital. The Genoskin team now recycles this skin into a patented testing model for cosmetic, pharmaceutical and chemical companies as well as research institutions. The retrieved skin is placed in a testing well that contains a special biological matrix to keep the skin alive for several days.

Unlike animal skin, bioprinted skin or skin that is grown in laboratories, Genoskin’s skin tissue model contains real, live human skin to study drug and compound toxicity and efficacy on a model that is as close as possible to in vivo human skin. “Animal testing is inefficient, time-consuming, expensive and increasingly perceived as unethical. We believe our technology marks a turning point. Not only do our human skin models address all these issues, they also help eliminate the major problem of efficacy and toxicity issues that arise due to differences between animal and human tissue,” said Pascal Descargues, founder and CEO of Genoskin. “Our skin models help academic institutions, pharma, cosmetic and chemical companies obtain more predictive results in order to lower R&D costs.”

A growing number of countries prohibit the use of animals to test cosmetic products, such as within the EU and in India. In the US, animal testing is an increasingly controversial topic. Moreover, as animal tissue differs from human tissue in many aspects, a large majority of the drugs that are validated on animals during preclinical studies will never reach the market(1,2), mainly due to toxicity and efficacy issues in humans.

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