Bans and other legal proposals to move away from animal testing are not news to the personal care industry. In recent years, for example, countries including China, Turkey,South Korea and Australia have announced their plans to follow in this direction.

As such, efforts have been directed at developing non-animal test assays. And while some alternatives have been identified, not all animal tests are easily replaced; skin sensitization is one of these.

Fortunately, a new study published in Toxicology In vitro describes a skin sensitization test based on non-transformed HaCaT cells. Previously, it had been shown to predict keratinocyte activation by sensitizers with 75% sensitivity, 83% specificity and 77% accuracy. The present study confirmed its intra- and inter-laboratory reproducibility and predictivity of sensitizers…/…

Read more…

Recent Posts

ZOOM#32 – Deep dive into the neurosensory claims

Dear readers, Welcome in this 32nd edition of the ZOOM, your go-to resource dedicated to…

L’Oréal sells Decléor and Saint-Gervais Mont Blanc, turns focus to Indian beauty market via Personal Care Insights

L’Oréal is offloading Decléor and Saint-Gervais Mont Blanc to the French group Cospal. The two…

Pola Chem develops personalised skin models with urine-derived iPS cells via Cosmetics Design Asia

Pola Chemical Industries unveils personalised skin models created from urine-derived induced pluripotent stem cells (iPS),…