Itching sensation and neuronal sensitivity of the skin: Neurometer® CPT Neurodiagnostic Testing Equipment For Soothing Claims by Neurotron Usa

Skin Res Technol. 2016 Feb;22(1):104-7. doi: 10.1111/srt.12236. Epub 2015 Aug 6.

Abstract

BACKGROUND
Sensitive skin is a universal term in the field of cosmetology. In addition, the development and demand for sensitive skin cosmetics is increasing. However, there is no appropriate method for detecting sensitive skin. 

METHODS

We analyzed the relationship between the frequency of response at each sensation (stinging, burning, and itching) during a lactic acid sting test and the current perception threshold (CPT) value of each frequency.

To reconfirm this relationship, we analyzed differences of the CPT value (5 Hz) between the itch responder and non-itch responder groups.

 

RESULTS

here is a significant correlation between itch sensation and CPT values of 5 Hz. The itch responder group showed significantly lower sensory perception value of 5 Hz than the non-itch responder group.

 

CONCLUSION

The CPT value (5 Hz) can be used for scanning for itching sensations when a cosmetic or its ingredients possibly cause the sensation.

 

Neurometer CPT/C
Manufacturer: Neurotron, Inc. Baltimore Maryland USA

The Neurometer CPT/C testing system utilizes distinct frequencies of constant current stimuli to measure perception thresholds of 3 major subpopulations of cutaneous sensory nerve fibers. Its ability to measure small fiber function makes the patented Neurometer uniquely suitable for evaluating skin irritation, sensitization, and itch perception. “Sensitive” skin test subjects are identified easily by comparing their baseline scores to established normative data. A full range of specially designed electrodes allows for the testing of any cutaneous or mucosal surface.

The Neurometer® CPT® is a unique neurodiagnostic device that painlessly evalutes the functioning of small unmylenated (C), small myelinated (Aδ) and large myelinated (Aβ) sensory nerve fibers at any cutaneous site. It’s sensitive to both hypoesthetic and hyperesthetic abnormalities and more than 800 peer reviewed research publications document its diagnostic capabilities. Since receiving FDA clearance in 1986, more than a million CPT® tests have been conducted around the world

Evaluates more than 90% of sensory nerve fibers (types Aβ, Aδ and C) using a standardized double-blind (p<0.006) automated test procedure .

Quantifies hyperesthesia/neuritis through hypoesthesia/neuropathy and monitors the progression of nerve regeneration.

Tests distal cutaneous finger and toe sites permiting earliest possible detection of nerve damage from diabetes, carpal tunnel syndrome, spinal injury, sciatica, and radiculopathy, polyneuropathy and other neuropathic conditions.

Measures sensory nerve function at any cutaneous site including mucosal surfaces such as the palate and the bladder.

CPT® measures are not affected by skin temperature, edema or electromagnetic interference unlike traditional electro-diagnostic and biopsy procedures.

Painless, non-invasive and non-aversive procedure is easy to perform and safe and harmless for clinical and laboratory use.

Nociceptive, rapid screening, computer automated and manual testing modes are also available.

Portable and battery powered device does not require special shielding or environmental conditions.

Neuval® CPT® software evaluates measures based on established norms, stores patient test results and prints reports.

Neuval® CPT® software evaluates measures based on established norms, stores patient test results and prints reports.

 

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