13 May 2025
An intriguing interplay between skin bacteria and UV radiation reported in the Journal of Investigative Dermatology paves the way for microbiome-aware sun protection
The skin microbiome plays an important role in health and disease. Researchers have now substantiated that certain skin bacteria can protect us from the sun’s ultraviolet (UV) radiation specifically by metabolizing cis-urocanic acid using an enzyme called urocanase. This enables the skin’s ability to fine-tune how it responds to UV radiation The findings of the study in the Journal of Investigative Dermatology, published by Elsevier, provide a striking case study that demonstrates the ability of the skin microbiome to remodel host immune functions.
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