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Newtone Solution for Wrinkles analysis: How to Measure Ground Truth by Newtone

2 January 2021

The Newtone family of solutions specializes in creating and developing increasingly powerful customized interpretation algorithms and acquisition systems, to help Cosmetic Industry to Innovate, Explore and Develop new products for all countries.

One challenge addressed by Newtone is to develop solutions enabling to measure “ground truth”: what the consumers actually see in the mirror. To help investigate wrinkles, Newtone developed innovative optical solutions and algorithms, for a combined approach using full face visible light imaging and local 3D imaging.Imaging systems and analysis algorithmsColorFace is a full-face imaging system, for high resolution and standardized image acquisition, under 7 lighting modes including one illustration mode “open eyes”). It is commonly used in clinical trials.  Connected to a dedicated cloud application (CiPaaS – Clinical Image Processing as a Service), it provides direct automatic and highly secured backup of images wherever the study takes place, all over the world.

About ColorFace image analysis, Newtone’s original approach is to prove product efficacy correlated with the human perception. Therefore, analysis parameters are conspicuous (visible) ones. Algorithms are developed to adapt automatically to the type of panel (specific and validated algorithms for different groups of origins), to fit with wrinkles typologies (specific and validated algorithms for nasogenian folds, eye contour, lips contour, forehead etc…) and finally to roughness severity (specific and validated algorithms for line marks, fine lines and wrinkles). All algorithms are developed to be correlated with clinical grading and reflect ground truth (using Newtone PhotoScale online solution for image grading).

Newtone likes to advise and offer a combined analysis of whole face wrinkles to bring more value to product performance investigation.New born SkinCam is a new nomadic solution for skin evaluation, including analysis of skin micro-relief in 3D. It can be handed over to the subject on the day of inclusion, at the clinical laboratory, for image acquisition and additional local measurements at home, when the laboratory is closed (early morning, every day, late evening, etc.). It provides additional information to ColorFace full face acquisitions by focusing on selected and localized areas, like wrinkles. Its different lighting modalities, as well as 3D for roughness analysis, can be used to acquire images of any area of the face and body skin.

Skin smoothness improvement can then be assessed by 3D analysis integrated on the whole surface of acquisition.Clinical GradingWith PhotoScale, one smart and user-friendly online service for clinical grading, Newtone also brings a supporting solution for clinical experts willing to grade the wrinkles and sagging under standard and reproductible conditions, on standardized images from all over the world. Randomization, image preparation (crops, zooms, morphings etc..), flexible image display and grading options, data export, statistics. This is an all in one packaged solution for smart remote image grading. Images can be acquired with Newtone solutions or independently coming from other imaging systems.What about AI for wrinkles assessment? Artificial Intelligence is being used in Newtone since several years now, to improve wrinkle segmentation algorithms but also develop customized automatic grading tools for skin characterization and product performance prediction.
Newtone’s Average face solution is one way to valorize anti-wrinkle product performance, with customized impactful visuals (article illustration: Newtone average face – ColorFace profile views).

Read the complete FOCUS#3: Focus#3 Anti-aging Clinical Testing.v2

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