Beyond self-reports of sensitive skin syndrome and related compromised skin conditions, the underlying factors of this affliction have been largely unknown—until now. Procter & Gamble (P&G) and 23andMe research has uncovered genetic associations to the syndrome.

Their work, published in Cosmetics, utilized genome-wide association studies (GWAS) in 23,426 unrelated participants of European ancestry from the 23andMe database. These subjects were assessed for self-declared sensitive skin and other skin conditions and diseases using an online question­naire. Respondents were divided into non-sensitive skin and sensitive skin groups; the former serving as controls.

In sensitive skin individuals, three significant points in the genome (foci) and seven suggestive foci were identified. Of the three most significant, all have been associated with pigmentation and two have been associated with acne.

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Published via Cosmetics&Toiletries , June 25, 2020