Phenocell/Axol is building human-relevant pain, sensory and peripheral neurotoxicity models with iPSC-derived sensory neurons by Phenocell via ZOOM#32

Phenocell axoCells human iPSC-derived sensory neurons express nociceptive ion channels such as Nav1.7, Nav1.8, Nav1.9, TRPV1, TRPM8 and TRPA1. They demonstrate functional relevance across multiple assays, including capsaicin and menthol treatment, thermoception and neurite outgrowth with paclitaxel.

These neurons are designed for advanced in vitro model formats including co-culture, microfluidics devices and organ-on–chip platforms. Manufactured in an ISO 9001:2015-accredited production facility, they meet excellent ISSCR Standards compliance. Additionally, the Maximizer supplement allow faster development.

Han X. et al, Toxics (2024) ‘s study is a prime example of how Axol’s human iPSC-derived sensory neurons can provide invaluable insights into drug safety, helping researchers better predict neurotoxicity.

With a full complement of offerings and decades of in-house expertise, let us know what we can do to help by emailing us at operations@axolbio.com.

CONTACT

www.phenocell.com

Helene Leménager

helene.lemenager@phenocell.com