As part of the Skin Biology Network of the region of Lyon, France, initiated in 2016 by the European Center of Dermocosmetology (CED) and the Lyonbiopôle healthcare competitiveness cluster, the second annual thematic day on Skin Ageing gathered 130 people last September 25 in Lyon. The event highlighted the Skin Biology expertise, technologies, and collaborative projects developed by public and private players.

First, Marie-Thérèse Lecci, of the Grenoble university hospital, reiterated the clinical aspects of skin ageing. “Skin ageing is influenced by two main factors: one is intrinsic and related to our biological clock, the other is extrinsic and depends on the sun, tobacco, pollution, our diet, and drugs.” The list of impacting criteria is long and completed by lifestyle changes. Recent studies conducted by Gattefossé showed that screen-related light stress slows down the cell metabolism and causes important damage on the ATP.

Following up skin ageing

Skin ageing can be followed up with “-omic” analyses, which help understand physiological mechanisms and identify relevant biomarkers. As Mathieu Hébert, of Laboratoire Hubert Curien, explained, contact-free, non-invasive volume imaging makes it possible to visualize the dermo-epidermal junction. “We have also modelled an average face to characterize the ptosis phenomena based on spectral and hyperspectral imaging,” he emphasized.

The CEA evaluates rosacea and complexion radiance by Diffuse Reflectance Spectroscopy.

Then, Catherine Bosser, of the Lyon École Centrale Laboratory of Tribology and Systems Dynamics (LTDS), suggested the SILT (Skin Index of Living Tissue) based on the elastin/collagen ratio calculation, for which a patent was registered.

Read more…