The skin as a barrier is a popular belief that hardly matches the experimental factuality. The skin is the outer part of the body and harbors several physiological functions. It participates in the immu balance and exerts tactile functions. Its enzymatic panoply accompanies or opposes the settlement of those microorganisms that constitute the surface microbiome, and it is kept elastic, flexible a The skin is the largest organ of the human body.

It has a surface of about two square meters and weights a couple of kilograms or so. Some scientists say that the skin is the envelope that contain inside in and the outside out. Of these definitions, the first one is the most simplistic one and the second one is the furthest one from the truth. It is experimentally observed that the skin regulates has been shown that the epidermis and the upper dermis take up oxygen from the surroundings, and not only from the blood vessels.1 It is also well known that water vapor crosses the skin. This several devices enable one to determine how many grams of water vapor cross the skin per square meter per hour.

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