Skin Sensitisation OECD 497 Guidelines for the Testing of Chemicals, Section 4

OCDE/OECD497 Adopted 9 June 2021 OECD GUIDELINE FOR TESTING OF CHEMICALSGuideline on Defined Approaches for Skin Sensitisation

This Guideline was developed with the input of an OECD Expert Group on Defined Approaches for Skin Sensitisation (EG DASS) comprised of scientific experts from regulatory agencies, validation bodies, non-governmental organisations, and industry. 9.Three rule-based DAs are included in this Guideline, and are described with respect to their intended regulatory purpose: hazard identification, i.e. discrimination between skin sensitisers and non-sensitisers (1.4.Part I), or potency sub-categorisation (1.6.Part IIPart II). The DAs included in Part II are also suitable for hazard identification.The evaluation and review of the DAs are described in detail in the Supporting document to the Guideline (GL) on Defined Approaches (DAs) for Skin Sensitisation.