Vitamin B12 supplements have been shown to lead to acne development, but the mechanism behind this effect has remained unexplored. Now, Kang et al. show that transcriptional changes in the skin microbiota contribute to vitamin B12–induced acne. Supplementing patients with vitamin B12 reduced the expression of vitamin B12 synthesis genes in Propionibacterium acnes and altered the transcriptome of the skin microbiota, resulting in the production of inflammation-inducing porphyrins. These studies demonstrate a clear link between changes in the skin microbiome and disease pathology.
Link to Science translational medecine
Roger Guillemin identified the molecules in the brain that control the production of hormones in…
In 2007, Sinclair wrote the article “Healthy Hair: What is it?” in which he stated,…
We spoke to John Chave, director-general at trade body Cosmetics Europe, about changing regulations, what’s…