Tissue injury induces metabolic changes in stem cells, which likely modulate regeneration.
Using a model of organ regeneration called wound-induced hair follicle neogenesis (WIHN), we identified skin-resident bacteria as key modulators of keratinocyte metabolism, demonstrating a positive correlation between bacterial load, glutamine metabolism, and regeneration. Specifically, through comprehensive multiomic analysis and single-cell RNA sequencing in murine skin, we show that bacterially induced hypoxia drives increased glutamine metabolism in keratinocytes with attendant enhancement of skin and hair follicle regeneration.
Roger Guillemin identified the molecules in the brain that control the production of hormones in…
In 2007, Sinclair wrote the article “Healthy Hair: What is it?” in which he stated,…
We spoke to John Chave, director-general at trade body Cosmetics Europe, about changing regulations, what’s…