Fragrances are important contact allergens; however, investigation of their skin sensitization potency has been challenging in new approach methods (NAMs). Many fragrance chemicals are susceptible to autoxidation or can be metabolized by enzymes constitutively expressed in skin keratinocytes. Strong sensitizers can be formed in both of these processes. Further, keratinocytes can modulate the dendritic cell (DC) activation and maturation potential, a key event in the acquisition of contact allergy.
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The Annual International Professional Symposium returns in 2025! Live or Online Register: click here Organized by Cosmet’in Lyon and Skinobs, Cosmetotest…
The Annual International Professional Symposium returns in 2025! Live or Online Register: click here Organized by Cosmet’in Lyon and Skinobs, Cosmetotest…
The Annual International Professional Symposium returns in 2025! Live or Online Register: click here Organized by Cosmet’in Lyon and Skinobs, Cosmetotest…