In its “Toxic Free Environment” strategy, the European Commission wishes to propose new hazard classes and new criteria in the CLP regulation in order to fully take into account environmental toxicity, persistence, mobility and bioaccumulation. Ecotoxicological assessment is therefore a fundamental issue, which can now be based on the new methodological approaches (NAM), known as “non-animal approaches”. These methods include in-silico, in chemico, in-vitro and ex-vivo methods and are based on mechanistic prediction models. This information can then be used in regulatory decisions regarding the use of chemicals.When no in-vitro or in-vivo study results are available for a substance, it is possible to use some of these NAMs to predict the toxicity of substances. The “Read Accros” method is one of the tools that we have put in place to provide a global view of the toxicity of a substance, whether on the environment or health.
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