The skin is the outermost protective barrier of the human body. Its role is to protect against different physical, chemical, biological and environmental stressors.
The vast majority of studies have focused on investigating the effects of single environmental stressors on skin homeostasis and the induction of several skin disorders, such as cancer or ageing. On the other hand, much fewer studies have explored the consequences of the co-exposure of skin cells to two or more stressors simultaneously, which is much more realistic.
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