Ingredient and Ingredient Effects Characterization by Phylogene

The discovery of new ingredients is unlimited. Plants extracts are the most used for years, and now new extracted active ingredients are sought in algae or bacteria, the latter called posbiotics. Concretely, it can be organic acids, peptides, proteins, polysaccharides or enzymes.

Most of these ingredients can be characterized using the new tools offered by mass spectrometry.

Skin is the largest organ to repel attacks from external agents and functioning as both a physical and immunological barrier. Its glandular nature, bacteria rich composition and rather rapid cell turnover is propitious for a wide range of innate and adaptive immune functions.

Effects characterization

Daily traumatized by naturally occurring abiotic stress (UV induced Oxidative stress, blue screen, cigarette smoke, pollutants) and physical traumas (inflammation, disruption of cell integrity), skin regeneration is paramount. “Decreased DNA damage; reduced inflammation; dynamic regulation of cell-cell and cell-matrix interaction; increased cell motility; increased lipids metabolism; increased migration and wound healing” are claimable phenomenon reached by proteomics, metaproteomics and phosphoproteomics analysis when associated with bioinformatics protocols.

At Phylogene, while metaproteomic analysis can unravel functional interactions between microbiota and hosts, phosphoproteomics can unravel cosmetics / dermocosmetic treatment benefits, at the cellular level.

Ingredient characterization

The discovery of new ingredients is unlimited. Plants extracts are the most used for years, and now new extracted active ingredients are sought in algae or bacteria, the latter extracts now called posbiotics. Concretely, they can be composed of organic acids, peptides, proteins, polysaccharides or enzymes.

Most of these ingredients can be characterized using the new tools offered by mass spectrometry. Polysaccharides remain a challenge due to their complexity but the others are easy to identify and quantify. Particularly at Phylogene, we also offer a way to anticipate the potential of allergenicity by comparison with known allergens.

Please find the website : www.phylogene.com