Special Preclinical Day on Endocrine Disruptors and In-vivo and In-vitro Testing: 26th May

Friday 26th 2023

From 8 am to 4.30

Cosmetotest Day – Preclinical Testing

1st Session: The place of organoids, spheroids, and organ-on-chips

• Vascularized skin organoids as models for skin pathologies, Dr Xavier GIDROL, CEA Grenoble.
• Advantages and limitations of 3D spheroids platforms for preclinical applications, Marisa MELONI, Vitroscreen.
• Advanced computer-connected 3D printed human skin models, Colin MC GUCKIN, CTIBiotech.
• Skin-on-a-chip models: an innovative and relevant in-vitro platform, Alexandre GUICHARD, Netri.

2nd Session: Endocrine disruptors evaluation

• Dr Christine LAFFORGUE – Université Paris Saclay.
• Skin absorption of thyroid-disrupting anions from concentrated aqueous solutions. Effects of mixing, Pr Marie-Alexandrine BOLZINGER, LAGEPP.
• A new strategy to detect substance binding to a set of endocrine receptors in silico methods, Zlatomir TODOROV, KREATiS.

3rd Session: Parallel of in-vitro and in-vivo testing

• Pr Dominique SIGAUDO-ROUSSEL, LBTI and Amélie THEPOT, Labskin Creations.
• Advantages and limitations of vitro/vivo approaches to sun protection, Anna LUDWIKOWSKA, Eurofins Dermscan.
• Epidermic stem cell orchestrates skin firmness and radiance thanks to their anchorage to the dermal epidermal Junction, Anne-Laure BULTEAU, LVMH Perfumes & Cosmetics.
• Use of skin explants to study complex skin mechanisms before clinical strategies, Céline LAPERDRIX, Codif International.