Strips Proteomics Analysis Breakthrough by Phylogene

13 April 2023

In cosmetics, stripping remains the more efficient and easy way of sampling, although these sample types present significant technical challenges for proteomic analysis. From samples preparation to extraction, several critical steps are to be taken care of. Glue, plastic polymers are major contaminants that must be dealt with before digestion and mass spectrometry analysis. To overcome these technical issues and for continuous improvement in dermo-cosmetics, PHYLOGENE developed new “PAC and iST” techniques for skin proteomics. When multiple D-Squames were previously necessary, only 1 D-Squame is now enough for an improved recovery yield of proteins! Just few D-Squames are now suitable to obtain proteins identification and function, making the characterization of both skin barrier function and superficial inflammation easier when paired with bioinformatics analysis.

D-Squame with “PAC and iST” techniques for skin proteomics, to characterize skin barrier function and superficial inflammation.

High-resolution nano LC-MS/MS quantitative proteomics and CORAVALID™ data processing, the efficient tools for discovery

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