Risk assessment of allergic sensitization and allergic reaction with new ingredients by Phylogene via ZOOM#32

8 January 2025

The ingredient industry is rapidly growing, fueled by demand for natural food, cosmetics, and innovative products using plant extracts, probiotics, and algae extracts. However, proteins from foreign species may trigger immune responses, leading to allergic sensitization.

PHYLOGENE specializes in advanced allergen risk assessment, combining cutting-edge technologies with expertise. Using high-resolution nano LC-MS/MS proteomics, PHYLOGENE identifies allergenic peptides through homology analysis with known allergens and evaluates neoallergen risks.

Their proprietary CORAVALID™ process assesses sensitization potential on cell lines like dendritic cells and keratinocytes. Additionally, PHYLOGENE offers quantitative inhibition of allergen-specific IgE antibodies (ELISA), providing comprehensive, regulatory-compliant solutions for allergen safety in complex ingredient mixtures.