23 May 2025
Gattefossé and Ambiotis have found that when pro-resolving lipid mediators become unbalanced they contribute to skin aging. The French companies’ joint research unveiled that these lipids become unbalanced in aged skin, disrupting cell communication and contributing to inflammation and tissue breakdown.
The research has increased the scientific understanding of skin aging, supporting Gattefossé in developing future cosmetics ingredients.
As skin ages, its ability to maintain balance and recover from stressors declines. The partnership found that certain lipid molecules, known to help resolve inflammation and restore tissue homeostasis, also play a role in this process.
Nicolas Bechetoille, head of Skin Biology Research at Gattefossé, says: “It is becoming essential to rethink cosmetic intervention through the lens of a more integrative anti-aging approach. The tissue integrity of the skin can no longer be viewed solely in terms of the balance between synthesis and degradation of extracellular matrix components.”
“Targeting pro-resolving bioactive lipids is now a key strategy to preserve skin health and effectively combat aging within a holistic, healthy aging framework.”
