The Challenge
Dermal interstitial fluid, as opposed to the bloodstream, is not under positive pressure. The fluid isn’t easy to sample. All parts of a system intended for sampling of dermal interstitial fluid need to be highly optimized and work in conjunction for an efficient sampling process.
Ascilion has spent over a decade refining every part of the system from the needle chip to the instrument controlling the process via the method for how the parts fit together with maintained sterility.
Dermal Interstitial Fluid
Biomarkers found in dermal interstitial fluid, a compartment close to cell activity, are often more relevant for analysis compared to those collected from blood sampling.
Dermal interstitial fluid is still largely unexplored because it has traditionally been very difficult to access. Furthermore, sampling processes have caused pain and discomfort, often resulting in an unwanted alteration of the content of the sample due to use of for instance local anesthesia or simply the invasive nature of the method.
This all changes with the simplicity of Ascilion’s microneedle system.
