By Mieke Meintjes
Gattefossé and Ambiotis have partnered to study how deregulated lipid mediators contribute to skin aging. The companies aim to translate their findings into novel skin care ingredients and formulations that work with the body’s systems to maintain skin health over time, offering a biological route to healthy aging, tapping into the longevity trend.
The research focuses on specialized pro-resolving lipids and how shifts in these compounds may disrupt skin homeostasis, leading to visible signs of aging.
The collaboration builds on the growing scientific consensus that skin aging stems from a “deeper, silent imbalance” at the cellular level rather than solely from external factors. This imbalance affects the skin’s ability to regenerate and defend itself, triggering inflammation and tissue degradation at a cellular level.
According to Marc Dubourdeau, CEO of Ambiotis, these lipids are key to restoring skin balance: “Encouraging the increased synthesis of these lipids is tantamount to reinforcing the skin’s own beneficial mechanisms, helping to prevent aging and preserve the skin’s vitality.”
By mapping molecular changes, Gattefossé and Ambiotis hope to create cosmetic ingredients that encourage the skin to produce more of its own pro-resolving lipids.
Editorial




