By Shamini Bundell & Nick Petrić Howe
Skin-permeable polymer shows promise at insulin delivery in animal experiments — plus, how the brain responds to unfamiliar languages.
A molecule that delivers insulin through the skin
Researchers have developed a skin-permeable polymer that can deliver insulin into the body, which they say could one day offer an alternative to injections for diabetes management. The skin’s structure presents a formidable barrier to the delivery of large drugs but in this work a team show that their polymer can penetrate though the different layers without causing damage. Insulin attached to this polymer was able to reduce blood glucose levels in animal models for diabetes at a comparable speed to injected insulin. While further research is required on the long-term safety of this strategy, the team hope it could offer a way to non-invasively deliver other large-molecule drugs into the body.
How language lights up the brain, whatever the tongue
The human brain responds in a similar way to both familiar and unfamiliar languages, but there are some key differences, according to new research — a finding that may explain why learning a language can be difficult. A study looking involving 34 people showed that listening to an unfamiliar language triggers similar neural activity to listening to their native tongue. The finding implies that human speech triggers a common reaction in the brain regardless of understanding. However, there were subtle differences when listening to a known language that may help explain how people actually understand words.
